| Building | Year completed / name changed | Architects / other notes |
| Administration Building (College Building) | 1912 / 1950-2000 | Brown & Vallance, 1910-12 |
| Administration Building | 1987 | Wiens, Johnstone, Regina, 1985-87 |
| Agricultural College (College Building) | 1912 | Brown & Vallance, 1910-12 |
| Agriculture Building | 1991 | Folstad & Friggstad, 1988-91 |
| Animal Husbandry / Veterinary Science Building | 1923 | |
| Animal Resources Centre | 1957 | |
| Animal Resources Centre - new building | 1986 | |
| Animal Science Building | 1959 | Stock & Ramsay, 1958-59 |
| Animal Science Building - renovations | 1989 | |
| Anthropology and Archaeology Building (Field Husbandry Building) | 1929 / 1997 | Brown, 1929 |
| Arts Building | 1960 | Shore & Moffat, 1958-60 |
| Arts Building - addition | 1964 | Shore & Moffatt, 1963-64 |
| Arts Building - addition (second classroom wing) | 1967 | Shore & Moffatt, 1965-67 |
| Arts Tower (Arts Building) | 1960 | Shore & Moffat, 1958-60 |
| Athabasca Hall | 1964 | Moody & Moore, 1963-64 |
| Biology Building | 1960 | Izumi, Arnott, Sugiyama, 1957-58 |
| Canadian Light Source - renovations to Linear Accelerator Laboratory | 1999 | |
| Cancer and Medical Research Building (Medical Research Building) | 1958 | Izumi, Arnott, Sugiyama, 1957-58 |
| Chapel of St. Chad | 1966 | Webster, Forrester, Scott, 1965-66 |
| Chemistry Annex | 1946 | |
| Chemistry Building | 1924 | Brown, 1922-24 |
| Chemistry Building - 2nd wing (Thorvaldson Building) | 1966 | Parkin, 1964-66 |
| Chemistry Building - Pharmacy addition | 1988 | Olfert |
| Chemistry Building - Spinks addition | 2003 | |
| College Building | 1912 | Brown & Vallance, 1910-12 |
| College Building - Convocation Hall renovations | 1987 | |
| College of Emmanuel and St. Chad (Emmanuel College) | 1912 / 1964 | Brown & Vallance, 1910-12 |
| Crop Science Building (Field Husbandry Building) | 1929 / 1962 | Brown, 1929 |
| Curling Rink | 1959 | |
| Dairy Barn | 1972 | |
| Dean of Agriculture's Residence (Faculty Club) | 1912 / 1912-1961 | Brown & Vallance, 1910-12 |
| Dental Clinic Building | 1979 | Holliday-Scott, Paine, 1976-79 |
| Diefenbaker Canada Centre (John G. Diefenbaker Centre) | 1979 / 1995 | Moore & Taylor, 1978-79 |
| Education Building | 1970 | Webster, Forrester, Scott, 1967-70 |
| Education Building - renovations | 1990 | |
| Ellis Hall | 1955 | Webster & Gilbert, 1952-55 |
| Emmanuel College | 1912 | Brown & Vallance, 1910-12 |
| Emmanuel College Residence (McLean Hall) | 1963 / 1963-1975 | Webster, Forrester, Scott, 1961-63 |
| Engineering Building - original building | 1912 | Brown & Vallance, 1911-12; Destroyed by fire, 1925 |
| Engineering Building - rebuilt | 1926 | Verbeke, 1925-26 |
| Engineering Building - second wing | 1913 | Brown & Vallance, 1913 |
| Engineering Building - Chemical Engineering addition | 2002 | |
| Engineering Building - addition | 1920 | Brown & Vallance |
| Engineering Building - west wing extension | 1938 | |
| Engineering Building - addition | 1947 | |
| Engineering Building - addition | 1962 | Webster, Forrester, Scott |
| Engineering Building - addition | 1981 | Forrester, Scott, Bower, Cooper, Walls, 1977-81 |
| Engineering Building - renovations | 1983 | |
| Faculty Club | 1912 | Brown & Vallance, 1910-12 |
| Faculty Club - fire, renovation and addition | 1966 | Malkin, 1965-66 |
| Faculty Club - renovation and addition | 1975 | |
| Farrowing Barn | 1915 | |
| Field Husbandry Building | 1929 | Brown, 1929 |
| Field Husbandry Building - addition | 1937 | Verbecke, 1937 |
| General Purpose Building - ca. 1968 | 1968 | |
| Geology Building | 1988 | BLM, Regina, 1984-86 |
| Griffiths Stadium | 1936 | |
| Griffiths Stadium - relocation | 1965 | |
| Griffiths Team House 1 | 1960 | |
| Griffiths Team House 2 | 1962 | |
| Grounds Greenhouse | 1963 | Izumi, Arnott, Sugiyama, 1962-63 |
| Gymnasium (Physical Education Building) | 1949 | Dept. of Public Works, Hanger & Martin, 1947-49 |
| Hangar Building - relocated on campus | 1947 | Dept. of Public Works; demolished, 1994 |
| Hantelman Building | 1962 | Izumi, Arnott, Sugiyama, 1962-63 |
| Health Sciences Building (Medical College Building) - A Wing | 1950 / 1986 | Webster & Gilbert, 1946-49 |
| Heating Plant | 1954 | Webster & Gilbert, 1953-54 |
| Heating Plant - addition | 1967 | Webster & Gilbert, 1967 |
| Heating Plant and Tunnels | 1950 | Webster & Gilbert |
| Horticulture Greenhouse - 1st | 1916 | Brown & Vallance, 1916 |
| Horticulture Greenhouse - 2nd | 1918 | |
| Interns' Residence (Hantelman Building) | 1962 | Izumi, Arnott, Sugiyama, 1962-63 |
| J.S. Fulton Laboratory (Virus Laboratory Building) | 1948 / 1964 | Webster & Gilbert, 1947-48; demolished, 1989 |
| John G. Diefenbaker Centre | 1979 | Moore & Taylor, 1978-79 |
| John Mitchell Building (Soils and Dairy Science Building) | 1949 / 1957 | Portnall & Stock, 1947-49 |
| Kinesiology Physical Activity Complex | 2003 | |
| Kirk Hall (School of Agriculture) | 1949 / 1962 | Portnall & Stock, 1947-49 |
| Law-Commerce Complex | 1967 | Holliday-Scott & Paine, 1965-67 |
| Linear Accelerator Laboratory | 1964 | |
| Little Stone School - relocated to campus | 1911 | |
| Livestock Pavilion | 1912 | Brown & Vallance, 1910-12; demolished, 1986 |
| Livestock Research Building | 1988 | EE Boehmer Engineering |
| Lutheran Theological Seminary | 1968 | |
| Main Barn | 1912 | Brown & Vallance, 1910-12 |
| Marquis Hall | 1964 | Izumi, Arnott, Sugiyama |
| McEown Park Residence Complex | 1970 | Stock Partnership |
| McLean Hall | 1963 | Webster, Forrester, Scott, 1961-63 |
| Medical Annex | 1946 | |
| Medical College Building - A Wing | 1950 | Webster & Gilbert, 1946-49 |
| Medical College Building - Health Science (B Wing) addition | 1971 | Moody & Moore, 1969-71 |
| Medical Research Building | 1958 | Izumi, Arnott, Sugiyama, 1957-58 |
| Medical Research Building - addition (third floor) | 1966 | Izumi, Arnott, Sugiyama, 1966 |
| Memorial Gates | 1928 | Brown, 1927-28 |
| Memorial Union Building | 1955 | Shore & Moffat, 1953-55 |
| Murray Building (Murray Memorial Library) | 1956 / 1974 | H.K. Black, 1954-56 |
| Murray Memorial Library | 1956 | H.K. Black, 1954-56 |
| Murray Memorial Library - south wing (Main Library) | 1974 | BLM, Regina, 1972-74 |
| National Research Council | 1947 | Verbecke, 1946-47 |
| National Synchrotron Facility (Canadian Light Source) - renovations to Linear Accelerator Laboratory | 1999 | |
| Newman Hall | 1927 | |
| Newman Hall - enlarged | 1943 | |
| Nobel Plaza | 1997 | Harder, University; Edwards, MVA, 1997 |
| Observatory | 1929 | Verbecke, University Architect, 1928-29 |
| Ogle Hall (St. Pius X Seminary) | 1966 / 1998 | Tinos-Kortes |
| Permanent Building for Temporary Use (General Purpose Building) - ca. 1968 | 1968 / 1968-1972 | |
| Physical Education Building | 1949 | Dept. of Public Works, Hanger & Martin, 1947-49 |
| Physical Education Building - addition (pool) | 1964 | Black, Larsen, McMillan |
| Physics Annex | 1946 | ; Destroyed by fire, 1979 |
| Physics Building | 1921 | Brown & Vallance, 1919-21 |
| Physics Building - addition | 1967 | Kerr, Cullingworth, Riches, 1966-67 |
| Place Riel Student Centre | 1980 | Ferguson, Folstad, Friggstad, 1978-80 |
| Poultry Science Building | 1918 | Brown & Vallance |
| Poultry Science Building - addition | 1956 | University architect |
| Power House | 1912 | Brown & Vallance, 1910-12; demolished, 1977 |
| Presbyterian Theological College (St. Andrew's College) | 1923 / 1923-1924 | Brown, 1922-23 |
| President's Residence | 1913 | Brown & Vallance, 1911-13 |
| President's Residence - renovations | 1989 | |
| Professor of Field Husbandry's Residence | 1911 | Brown & Vallance |
| Qu'Appelle Hall | 1916 | Brown & Vallance, 1914-1916 |
| Qu'Appelle Hall - addition | 1963 | |
| Royal University Hospital | 1955 | Webster & Gilbert, 1948-55 |
| Royal University Hospital - parkade | 1973 | |
| Royal University Hospital - addition | 1979 | Consortium, Saskatoon, 1975-79 |
| Rugby Chapel - moved to campus ca. 1913 | 1913 | |
| Rutherford Rink | 1929 | Verbecke, 1929 |
| Saskatchewan Hall | 1912 | Brown & Vallance, 1910-12 |
| Saskatchewan Research Council (Toxicology Research Centre) | 1958 / 1958-1984 | Izumi, Arnott, Sugiyama, 1957-58 |
| Saskatoon Cancer Centre | 1988 | Ferguson, Folstad, Friggstad, 1986 |
| Saskatoon selected as site for the University | 1909 | |
| School of Agriculture | 1949 | Portnall & Stock, 1947-49 |
| Soils and Dairy Science Building | 1949 | Portnall & Stock, 1947-49 |
| St. Andrew's College | 1923 | Brown, 1922-23 |
| St. Andrew's College - addition | 1962 | Webster, Forrester, Scott, 1959-62 |
| St. Pius X Seminary | 1966 | Tinos-Kortes |
| St. Thomas More College | 1956 | Webster & Gilbert, 1954-56 |
| St. Thomas More College - addition | 1964 | Gardiner, Thornton, Gather, 1962-64 |
| St. Thomas More College - addition | 1970 | Gardiner, Thornton, Gather, 1969-70 |
| Stone Barn (Main Barn) | 1912 | Brown & Vallance, 1910-12 |
| Thorvaldson Building (Chemistry Building) | 1924 / 1966 | Brown, 1922-24 |
| Toxicology Research Centre | 1958 | Izumi, Arnott, Sugiyama, 1957-58 |
| Victoria School House (Little Stone School) - relocated to campus | 1911 | |
| Virus Laboratory Building | 1948 | Webster & Gilbert, 1947-48; demolished, 1989 |
| W.P. Thompson Building (Biology Building) | 1960 | Izumi, Arnott, Sugiyama, 1957-58 |
| Western College of Veterinary Medicine | 1969 | Izumi, Arnott, Sugiyama |
| Western College of Veterinary Medicine - addition | 1981 | |
| Western College of Veterinary Medicine - addition | 1988 |